Bedfordshire and Luton Joint Formulary
Bedford Hospital NHS Trust
Bedfordshire CCG
Luton & Dunstable University Hospital NHS Foundation Trust
Luton CCG

 
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9 Nutrition and blood

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

09-01-04 Drugs used in autoimmune thrombocytopenic purpura

Anagrelide 0.5mg Xagrid®
Restricted

Restricted- prescribing by consultant Haematologists.


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Avatrombopag Doptelet®
Restricted

FOR ALL PRESCRIBING - Blueteq or high cost drug form required - see link from Formulary homepage.

RESTRICTED to prescribing in accordance with the following NICE TA(s):

Link  NICE TA 626 Avatrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure
 

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Eltrombopag 25mg, 50mg Revolade®
Restricted

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage.

Approved in accordance with NICE TA293 for the treatment of chronic immune thrombocytopenic purpura

N.B. May interfere with bilirubin and creatinine test results. See MHRA link for further information. Any clinical concerns contact the Clinical Biochemistry team on bleep 237.

Link  MHRA Drug Safety Update (July 2018): Eltrombopag (Revolade): reports of interference with bilirubin and creatinine test results
Link  NICE TA293: Eltrombopag for treating chronic immune (idiopathic) thrombocytopenic purpura (review of technology appraisal 205)
 

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Lusutrombopag Mulpleo®
Restricted

FOR ALL PRESCRIBING - Blueteq or high cost drug form required - see link from Formulary home page.

RESTRICTED to prescribing in accordance with the following NICE TA(s):

Link  NICE TA 617 Lusutrombopag for treating thrombocytopenia in people with chronic liver disease needing a planned invasive procedure
 

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Romiplostim Nplate®
Restricted
FOR ALL PRESCRIBING Blueteq or High cost drug form required see link from Formulary homepage.

Indicated for the treatment of chronic thrombocytopenic purpura in splenectomised patients

Recommended for the treatment of chronic immune thrombocytopenic purpura in accordance with NICE TA221

250microgram Injection
Link  NICE TA221: Thrombocytopenic purpura - romiplostim
 

Restricted Drug Red View adult BNF  View SPC online  View childrens BNF  HCD